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CPT Code 99385: Age Limit, Modifier 25 and Denials 2026

CPT Code 99385: Age Limit, Modifier 25, and Denial Fixes (2026 Billing Guide)

Category: Medical Billing

Posted By: Andrew Christian

Posted Date: Aug 11, 2026

CPT code 99385 reports an initial comprehensive preventive medicine visit for a new patient aged 18 to 39. Selection depends on two variables: the patient's age on the date of service, and new versus established status. Medicare doesn't cover it. Most commercial plans cover it once per year.

Field

Detail

Code

99385

Code type

Preventive medicine evaluation and management (E/M)

Patient status

New patient only

Age range

18-39 years at date of service

Selection basis

Age and patient status. Not time. Not medical decision-making.

Established equivalent

99395

Adjacent codes

99384 (12-17 years), 99386 (40-64 years)

Primary ICD-10

Z00.00, or Z00.01 when abnormal findings are present

Same-day E/M modifier

Modifier 25, appended to the E/M code

Modifier 33

Not required for services that are preventive by definition (CPT 2026)

Medicare coverage

Not covered. Use G0402, G0438, or G0439.

Typical commercial rate

$150 to $220, payer and contract dependent

Frequency

Once per year, calendar year or rolling 365 days by payer

Global period

None

Work enough of these denials and you'll see the same three rows fail over and over. Age, patient status, and the modifier on a same-day problem visit.

What Is CPT Code 99385?

CPT code 99385 covers an initial comprehensive preventive medicine evaluation and management service for a new patient between 18 and 39 years old. The American Medical Association maintains the descriptor. It pairs an age and gender appropriate history and exam with counseling, risk factor reduction, and orders for screening labs.

Search for the 99385 CPT code description and you'll find near-identical wording across coding references, because they all draw from the same AMA source. For the full code set and its update cycle, the AMA CPT resources page is the primary reference.

What a 99385 Preventive Visit Includes

  • Age and gender appropriate history covering personal, family, and social background
  • A physical examination scaled to the patient's age and sex
  • Counseling and anticipatory guidance on identified health risks
  • Risk factor reduction interventions such as tobacco or alcohol screening
  • Orders for age-appropriate laboratory and diagnostic procedures

The code doesn't cover diagnosis or treatment of an acute or chronic problem. If a provider works up a complaint during the visit, that's a second service carrying its own code and its own documentation.

One word in the CPT code 99385 definition causes more trouble than the rest. Comprehensive here doesn't mean the comprehensive exam from the 1995 or 1997 E/M documentation guidelines. It means appropriate to the patient sitting in front of you.

A 25-year-old's preventive exam looks nothing like a 4-year-old's. Reviewers know that. What they want in the note is evidence you scaled the visit to this patient, not a template that could belong to anyone.

99385 sits inside the preventive medicine CPT codes family, 99381 through 99397, split by patient age and by whether the patient is new or established. Patients call the visit an annual physical. The CPT code for annual physical exam billing changes with the patient's age, which is why no single code covers the whole schedule.

CPT 99385 Age Limit: 18 to 39 at the Date of Service

CPT code 99385 applies to new patients 18 through 39 years old on the date of service, not the scheduling date. A patient who turns 40 before the visit requires 99386. A patient still 17 requires 99384. Payer systems validate age against the code at submission.

An automated edit enforces the 99385 CPT code age limit. It fires before a human ever opens the claim, and it doesn't weigh how thorough the visit was against how old the patient is.

What Payers Do at the Age Boundary

UnitedHealthcare publishes the clearest answer in the industry. Its commercial age-based codes policy, version-dated August 1, 2026, takes the exact scenario in its published Q and A: a claim submitted with 99385 for a patient who is 17 years and 11 months on the date of service. The answer is a denial, because the patient's age falls outside the range assigned to that code. The provider may submit a corrected claim with the right age-based code.

Two details in that policy change how you work the denial. The rejection is automatic, and the remedy is a corrected claim. UnitedHealthcare treats the submission as a billing error, so the documentation you'd normally attach to an appeal won't move it.

Other payers write their own versions of the same rule. Premera publishes age-mismatch guidance for the preventive series. Check the reimbursement policy for each payer in your mix rather than assuming one rule covers all of them.

The 99385 CPT code description age limit question also shows up as a scheduling problem, not a coding problem. Running date of birth against date of service as part of eligibility verification before the visit catches these before a claim ever goes out. Flag any patient inside 60 days of an 18th or 40th birthday when the appointment is booked.

When one slips through, the remittance usually carries an age-inconsistency reason code alongside modifier and coding edits. Our guide to the CO-4 denial code walks through that family of rejections in detail.

New Patient or Established? The Three-Year Rule for CPT Code 99385

A patient is new if they haven't received professional services from the physician, or from another physician of the same specialty and subspecialty in the same group practice, within the previous three years. If they have, bill 99395 instead. The rule turns on specialty, not tax ID.

  • A patient moving between physicians of the same specialty in one group stays established
  • A patient not seen for three years and one day counts as new again
  • A physician who joins a practice and inherits a panel must check the group's billing history, not their own

The multi-specialty trap catches practices that think they're safe. CMS ties the definition to same specialty, not same tax ID, and its new vs established patient guidance spells that out. A group billing several specialties under one TIN needs specialty mapped correctly in scheduling, or the status determination fails before anyone opens the chart.

CPT 99385 vs CPT 99395

Both codes cover the same age band with the same clinical components and the same documentation burden. The only variable is whether this practice has seen the patient in the past 36 months.

Billers comparing the 99395 CPT code description against 99385 sometimes expect a clinical difference and don't find one. New patient codes usually pay a little more, because the provider builds the record from nothing instead of updating it. For the 40 to 64 band, our CPT 99396 billing guide covers the established-patient side of the same logic.

Mixing up CPT code 99395 with the new patient CPT code is one of the more frequent status errors in this family, and it produces a denial no appeal will reverse. The payer isn't questioning whether the visit was covered. The code on the line is wrong, so a corrected claim is the only route back.

Which Preventive Code Do I Use? 99381 Through 99397 by Age and Status

Two questions settle it. Neither one involves time spent, complexity, or how much the provider documented. Work them in order and you land on the right code from the preventive visit CPT codes family every time.

The Two-Question Code Selection Tree

Question 1. What is the patient's age on the date of service?

  • 18 to 39 years: continue to Question 2
  • 12 to 17 years: 99384 for a new patient, 99394 for established
  • 40 to 64 years: 99386 for a new patient, 99396 for established
  • 65 and older: 99387 for a new patient, 99397 for established

Question 2. Has this physician, or the same specialty in the same group, provided professional services in the past 36 months?

  • No: bill 99385
  • Yes: bill 99395

Preventive Visit CPT Codes by Age and Patient Status

Age band

New patient

Established patient

Under 1 year

99381

99391

1 to 4 years

99382

99392

5 to 11 years

99383

99393

12 to 17 years

99384

99394

18 to 39 years

99385

99395

40 to 64 years

99386

99396

65 and older

99387

99397

Anyone searching for an annual wellness visit CPT code by age is looking at this grid. The 99384 CPT code description and the 99387 CPT code description differ from 99385 in one respect only: the age band in the descriptor. Clinical content and documentation expectations stay constant across the series.

CPT 99385 vs CPT 99386

Both are new patient preventive visits with identical clinical components. The only variable is age on the date of service. The 99385 age limit runs 18 to 39. The 99386 CPT code covers 40 to 64.

Some published sources describe the 99386 CPT code description as covering new adult patients aged 18 and older. That reading is wrong, and following it would put a 25-year-old on 99386. The two age bands don't overlap. Check the birthday, then pick the code.

The CPT 99385 age limit and the boundary above it both sit on the date of service. A patient booked at 39 who walks in on their 40th birthday moves to 99386 that day.

Is CPT Code 99385 Time-Based or MDM-Based?

No. 99385 isn't time-based, and it isn't scored on medical decision-making. Code selection depends on two variables: the patient's age on the date of service, and new versus established status. Office visit codes 99202 through 99215 follow a different rule, leveled by time or MDM.

At the charge desk that ends one recurring argument. A provider who spends 45 minutes on a preventive visit bills the same code as one who wraps up in 20. Match the age, confirm patient status, move on.

Several coding references describe 99385 as a moderate-complexity encounter that varies with time spent and documentation level. That language belongs to problem-oriented E/M. Pasted onto a preventive code, it sends billing teams hunting for a time threshold the descriptor never contained.

One exception is worth knowing. If the provider addresses a separate problem during the same visit, that portion does get leveled by time or medical decision-making. That's a second code carrying modifier 25, and it changes nothing about how you select 99385. Our CPT 99204 time and MDM rules guide covers how that second code gets built.

CPT Code 99385 Documentation Requirements: The Five Required Components

CPT code 99385 requires documentation of five components: an age and gender appropriate history, a comprehensive physical examination, counseling and anticipatory guidance, risk factor reduction interventions, and orders for appropriate laboratory or diagnostic procedures. All five have to appear in the note to support the claim under audit.

  1. Age and gender appropriate history, covering personal, family, and social background plus a relevant review of systems
  2. Comprehensive physical examination scaled to an adult in the 18 to 39 range, including blood pressure and BMI
  3. Counseling and anticipatory guidance tied to the risks this patient carries
  4. Risk factor reduction interventions, documented with the patient's response
  5. Orders for laboratory or diagnostic procedures, with the clinical reasoning behind each one

Length doesn't decide this. A short note showing all five elements holds up better than a long one that skips counseling and pads the exam.

Where 99385 Notes Fail Audit

Reviewers pull the same three problems out of preventive charts over and over, and each one has a fix your team can apply this week.

  • Counseling recorded as a checkbox. Lifestyle counseling provided isn't documentation. Record what you discussed, which risk factor prompted it, and what the patient said back.
  • History copied forward. A reviewer spots a note that reads identical to last year's, and the EHR timestamp confirms it.
  • Preventive and problem work blended into one narrative when both services were billed. Separate the sections or expect a bundling edit.

For the 18 to 39 band, the counseling topics with the strongest evidence base come from the USPSTF A and B recommendations: tobacco use, unhealthy alcohol use, diet and physical activity, STI prevention, blood pressure screening, and depression screening. Build those into the template as structured fields and your providers won't have to hold the 99385 CPT code description in their heads.

Give a provider a free-text counseling box and you'll get a one-line entry. Structured prompts tied to the CPT code 99385 description produce a note that survives a records request.

ICD-10 Codes for CPT 99385: Z00.00, Z00.01, and the FY2026 Sequencing Rule

Preventive visits billed with CPT 99385 pair with Z00.00, the general adult medical examination without abnormal findings, or Z00.01 when findings are present. Under the FY2026 ICD-10-CM Official Guidelines, an exam that reveals an abnormality requires Z00.01 sequenced first, with a secondary code identifying what was found.

ICD-10 code

Description

When to use it

Z00.00

General adult medical exam without abnormal findings

Visit completed with no new or abnormal clinical findings

Z00.01

General adult medical exam with abnormal findings

An abnormality identified. Sequence first, then code the finding.

A 24-year-old comes in for a first physical and the blood pressure reads 148 over 94 with no prior diagnosis. Z00.01 leads. The elevated reading follows as a secondary code. Reverse that order and the payer reads the encounter as problem-oriented.

Losing the preventive designation costs the patient too. The visit drops out of the no-cost-sharing preventive benefit and lands on the deductible, which is how a routine physical turns into a surprise bill and a call to your front desk.

When Lab Results Aren't Back Yet

The FY2026 guidelines address the gap most references skip. Code assignment reflects what the coder knows at the time of coding. If no abnormal findings have surfaced because results are still pending, Z00.00 holds. The CDC ICD-10-CM FY2026 guidelines carry the full sequencing language.

Screening orders placed during the visit get their own supporting codes. Z01.411 and Z01.419 for gynecological exams, Z11.51 for HPV screening, Z13.220 for lipid screening. These sit alongside the primary Z00 code and never replace it.

Does Medicare Cover CPT 99385? No, and Here Is What to Bill Instead

Medicare doesn't cover CPT 99385. Routine physical examinations sit outside Part B by statute. CMS instructs providers not to bill 99381 through 99397 for Medicare wellness services and to use G0402 for the Initial Preventive Physical Exam, G0438 for an initial Annual Wellness Visit, or G0439 for subsequent visits.

Code

Service

Frequency

G0402

Initial Preventive Physical Exam, the Welcome to Medicare visit

Once, within the first 12 months of Part B enrollment

G0438

Annual Wellness Visit, initial

Once per lifetime

G0439

Annual Wellness Visit, subsequent

Once per 12 months

99385

New patient preventive visit, ages 18 to 39

Not covered by Medicare

The CMS Medicare Wellness Visits page carries the coverage language and the AWV clinical requirements. One detail matters for anyone building a workflow. The Annual Wellness Visit doesn't include a physical exam, so a provider who performs one and bills 99385 alongside G0439 will watch that line reject.

When a Medicare Patient Wants a Physical Anyway

CMS publishes a mechanic for this that most coding references leave out. When a provider furnishes a covered visit on the same occasion as a noncovered preventive medicine service, CMS treats the covered visit as furnished in lieu of part of the preventive service.

The practice may then charge the beneficiary for the noncovered remainder, calculated as the difference between the preventive service charge and the covered visit charge. That gives you a defensible number to put on the patient statement instead of writing the visit off.

On the ABN: CMS doesn't require an Advance Beneficiary Notice for services Medicare never covers by statute, though it encourages one when billing 99381 through 99397. Watch the form version. CMS posted an updated Form CMS-R-131 with a March 31, 2029 expiration, and the prior version stopped being acceptable after May 12, 2026. The CMS advance beneficiary notice page holds the current form.

Most 99385 claims never reach Medicare, since the age band tops out at 39. The ones that do usually involve a beneficiary under 65 who qualified through disability, or a Medicare Advantage plan the front desk read as commercial. Route by payer at check-in and the problem disappears. Our Medicare billing support guide covers the wider set of Medicare routing rules.

Billing CPT Code 99385 With a Problem Visit: Modifier 25 Rules

Yes, 99385 and a problem-oriented E/M can go out on the same date when the provider addresses a significant, separately identifiable problem beyond the preventive visit. Modifier 25 goes on the E/M code, never on 99385. The record has to show two distinct pieces of work, not one blended note.

A 27-year-old new patient comes in for her first physical. Halfway through, she mentions three weeks of knee pain that's limiting her at work. The provider examines the knee, orders imaging, and writes a separate assessment and plan.

That encounter produced two services. Bill 99385 with Z00.00 for the preventive work, and 99203 with modifier 25 and a knee diagnosis for the problem work.

The Three Documentation Elements Modifier 25 Requires

  1. A distinct chief complaint that falls outside the scope of the preventive visit
  2. Separate note sections a reviewer can read on their own and follow
  3. An E/M level selected on the problem work alone, not on the full encounter

Counseling a patient about smoking during a wellness visit is part of 99385. Diagnosing and managing a new complaint is not. Our CPT 99203 new patient E/M guide walks through how to level that second service on its own merits.

Can You Bill Two New Patient Visits on the Same Day?

Per CPT guidance, when a preventive medicine service and an office or outpatient service both happen at the same encounter for a patient who meets the new patient definition, both may be reported as new patient codes.

Reimbursement is a separate conversation. Plenty of payer systems carry an edit that denies a second new patient visit on the same date of service, and you'll see it come back. Follow the coding rule, expect the edit, and appeal with the CPT reference attached.

That gap between what the code set permits and what a payer pays is where billing teams lose confidence in their own coding. The rule didn't change. The payer built an edit around it.

Do the Diagnosis Codes Have to Be Different?

Coding sources split on this one, and both readings show up in search results. CMS guidance on modifier 25 says different diagnoses aren't required. What the payer needs is documentation supporting a separately identifiable service.

In practice, linking distinct diagnoses to each line reduces bundling edits and moves the claim through adjudication faster. Requirement and best practice aren't the same thing here, and knowing which is which keeps you from rejecting a valid claim internally. CMS confirms the same-day principle from the Medicare side on its CMS Annual Wellness Visit billing page, which allows a significant, separately identifiable E/M alongside the wellness visit.

Modifier 33 and Modifier 59 With Preventive Visits

Is Modifier 33 Required for CPT 99385?

No. Modifier 33 flags a service as preventive when that status isn't otherwise clear. CPT 2026 clarified that the modifier isn't required for services that are preventive by definition, and 99385 qualifies. Some payers still request it. Check the contract before appending it to every claim.

  • Modifier 33 attaches to the preventive service, never to a problem-oriented E/M billed alongside it
  • Appending it across the board without checking payer requirements buys nothing, and on some payers it triggers an edit

When Modifier 59 Applies

Modifier 59 marks a distinct procedural service. It isn't an E/M modifier, which is where the confusion starts.

A preventive visit that includes a Pap collection and a transvaginal ultrasound produces three lines. The preventive E/M may carry 25, the ultrasound may carry 59, and whether it does depends on the NCCI edit pair and the payer's own bundling policy.

Draw the line this way: 25 belongs on E/M services, 59 belongs on procedures. Immunizations ordered during the visit are separately reportable too, and our guide to immunization administration codes covers how those lines are built alongside a preventive visit.

CPT Code 99385 Reimbursement: What Commercial Payers Pay in 2026

Commercial reimbursement for 99385 runs between $150 and $220 per encounter as a national benchmark. The spread inside a single payer network is wider than the spread between payers. Contracted rates move with the payer agreement, geography, specialty designation, and place of service.

Payer

National average benchmark

Cigna

approximately $195

Aetna

approximately $156

Blue Cross Blue Shield

approximately $152

UnitedHealthcare

approximately $150

Medicare

Not covered

Why the Same Code Pays Two Practices Different Amounts

Published transparency-file data shows provider-level allowed amounts for 99385 under one national payer running from roughly $81 to $285. That's a 3.5 times spread inside a single network, and none of that spread reflects how the provider performed the visit.

Four drivers explain most of it, and you can act on all four: your contracted fee schedule, the geographic practice cost index for your area, the specialty designation carried on the claim, and whether the rendering provider bills under the group contract or an individual one.

That last driver catches practices after a hire. A new provider working under their own enrollment instead of the group agreement can sit at the bottom of that range for months before anyone compares the remits.

The 2026 Conversion Factor and a Non-Covered Code

For 2026, CMS finalized two conversion factors for the first time under statute: $33.5675 for practitioners participating in a qualifying Alternative Payment Model, and $33.4009 for those who aren't. Published sources that quote a single 2026 figure are quoting half the picture. The CMS 2026 relative value files carry both.

Medicare pays nothing for 99385, so the conversion factor looks irrelevant at first. Plenty of commercial contracts are written as a percentage of the Medicare fee schedule, which means the factor moves your commercial rate even on a code Medicare will never touch.

CMS also finalized an efficiency adjustment for 2026 that trims work RVUs by 2.5 percent across most services that aren't time-based. Preventive medicine codes aren't time-based, which puts them inside that adjustment. If your contract is Medicare-indexed, model it before renewal season. Payer-specific rules like UHC filing deadlines sit in the same category of detail that decides whether a clean claim gets paid.

How Often Can CPT 99385 Be Billed?

Once per patient relationship. 99385 is a new patient code, so a patient qualifies for it a single time with your practice and moves to 99395 for every preventive visit after that. The annual frequency limit built into preventive benefits governs 99395.

Calendar Year Against Rolling 365 Days

Two frequency models run across commercial payers, and knowing which one a plan uses decides whether the next visit pays.

  • Calendar year model. The benefit resets January 1. A patient seen in November becomes eligible again on January 2.
  • Rolling 365-day model. The benefit resets 365 days after the last date of service. A March 10 visit means no eligibility until March 10 the following year.

Book a patient one day early under a rolling model and the payer denies it without review. No appeal reverses that one, because the interval hasn't elapsed and the claim carries both dates.

Medicaid Frequency Limits Vary by State

State Medicaid programs set their own caps, and some publish a maximum number of preventive visits per year across a defined code set. Pennsylvania publishes one. Other states write different rules, and managed care organizations layer requirements on top. The Medicaid.gov benefits page explains the federal structure, but the number you need lives in your state provider manual and your MCO contract.

Why CPT Code 99385 Claims Get Denied, and How to Fix Each One

Most 99385 CPT code denials come from five causes: wrong patient status, age outside 18 to 39, a missing modifier 25 on a same-day E/M, a chronic disease code sitting in the primary diagnosis position, or submission to Medicare. Each one carries a distinct remittance code and a distinct fix.

Remittance code

What it means here

Root cause

Fix

CO-4

Procedure code inconsistent with the modifier, or a required modifier is missing

Same-day E/M billed without modifier 25

Resubmit a corrected claim with 25 on the E/M line

CO-97

Service is included in the allowance for another service already adjudicated

Preventive and problem E/M bundled together

Appeal with separated documentation showing distinct work

PR-49

Routine exam or screening, not a covered benefit

Preventive benefit already used, or the plan excludes routine exams

Verify the benefit period, then bill the patient with prior notice

CO-6

Procedure inconsistent with the patient's age

Age outside 18 to 39 on the date of service

Recode to 99384 or 99386 and resubmit

CO-16

Claim lacks information needed for adjudication

Missing or invalid diagnosis pairing

Correct the Z-code sequencing and resubmit

CO-50

Payer doesn't consider the service medically necessary

Chronic disease code in the primary position

Resequence with Z00.00 or Z00.01 first

Working one denied preventive claim recovers one claim. Finding the pattern behind it stops the next ten, which is what you get from real denial management services. A practice running 40 preventive visits a month at a 12 percent denial rate loses roughly five claims every cycle to problems that repeat.

Age Mismatch Denials Can't Be Appealed

The payer classifies an age mismatch as a coding error, not a coverage dispute. No documentation argument recovers it. Recode and resubmit is the only route, which makes prevention the whole strategy: run date of birth against date of service during eligibility, not at billing.

That single check also protects against the 99385 CPT code age limit problem in reverse, where a patient books at 39 and presents after turning 40.

Bundling Denials on Same-Day Billing

A bundling rejection on a preventive plus E/M pair usually means the note read as one service to the reviewer. Build the appeal around a record that separates the two components on the page, and attach a cover letter pointing to which note section supports which line. Our guide to the CO-97 denial code covers the appeal structure in detail, and CO-50 medical necessity denials follow a different appeal path worth knowing before you write the letter.

Preventive Denials Aging Past 60 Days

Recovery odds drop after 60 days, and timely filing windows close behind them. Preventive denials sit longer than most because each one looks small on its own. You won't prioritize a $180 claim on a Tuesday afternoon with three $4,000 claims beside it.

Multiply that by a year and you're looking at real money. Denials sitting past 60 days need a structured AR follow-up on aged claims process with defined timelines, not a sweep whenever someone finds an afternoon.

Can CPT 99385 Be Billed Via Telehealth?

Coverage varies by payer. Since the COVID-19 public health emergency ended, telehealth coverage for preventive medicine codes has moved through a series of extensions rather than settling into a uniform standard. Verify the specific payer policy before you schedule a preventive visit as telehealth.

A clinical constraint sits underneath the coverage question. CPT 99385 requires a comprehensive physical examination, and a fully remote encounter can't deliver one. Practices billing it this way should document which exam components the provider performed and which ones the format prevented.

Place of service and modifier selection change with the delivery method too. Our 2026 telehealth CPT codes guide covers the current POS and modifier rules across Medicare and commercial payers.

Preventing CPT 99385 Denials Before the Claim Goes Out

Nearly every denial covered above traces to a decision made before the provider walked into the room. You'll recover more on CPT code 99385 through front-end discipline than through back-end coding skill, because the two variables that select the code both get set at scheduling.

The Five-Point Pre-Visit Check

  1. Verify eligibility and confirm the preventive benefit hasn't been used in the current period
  2. Check date of birth against date of service, not against the scheduling date
  3. Pull the last date of service to settle new against established status
  4. Route Medicare patients to the AWV pathway before the appointment gets booked
  5. Confirm the documentation template prompts all five required components

Where the Errors Start

Coders catch a fraction of these. The rest originate at scheduling, where nobody pulled the last visit date, and at the front desk, where nobody noticed the patient turns 40 next week. Fixing the coding step alone leaves both sources running. Place of service codes belong on that same pre-visit checklist, since a wrong POS on a preventive claim produces its own denial family.

Choosing an RCM Partner for Preventive Visit Billing

Four criteria separate a billing partner who handles preventive visit CPT codes well from one who processes them like any other line item.

  1. Payer-specific frequency knowledge, because calendar year and rolling 365 models aren't interchangeable
  2. Modifier management with a verification step ahead of submission, not manual application at charge entry
  3. Denial resolution running on defined timelines instead of a general queue
  4. Percentage-based pricing that ties the partner's revenue to your collections

MedSole RCM provides full-service medical billing at 2.99% of collections and provider credentialing at $99 per payer, with no setup fees and no long-term contracts. Both services cover all 50 states and operate inside the practice's existing EHR, so your staff never learns a new platform.

For a practice collecting $50,000 a month, that rate works out to $1,495. The same scope at a 6 percent billing company costs $3,000 before add-ons.

CPT Code 99385: Frequently Asked Questions

What is CPT 99385 used for?

99385 reports a new patient preventive medicine visit for ages 18 to 39. It covers an age and gender appropriate history, a comprehensive exam, counseling and anticipatory guidance, risk factor reduction interventions, and orders for screening labs or diagnostics. The code doesn't cover diagnosis or treatment of an acute or chronic problem, which requires a separate E/M code.

What is the age range for CPT 99385?

18 through 39 years, measured on the date of service rather than the scheduling date. A patient under 18 requires 99384. A patient 40 or older requires 99386. Payer systems validate age against the code at submission, and the 99385 age limit produces a coding error no appeal reverses. The 99385 CPT code description age limit appears in the AMA descriptor itself.

What is the difference between 99385 and 99386?

Both are new patient preventive visits with identical clinical components and identical documentation requirements. Age on the date of service is the only variable. 99385 covers 18 to 39. The 99386 CPT code covers 40 to 64. Some published sources describe the 99386 CPT code description as covering patients 18 and older, which would put a 25-year-old on the wrong code and produce a denial.

Is 99385 a time-based code?

No. Selection depends on age and patient status alone. The code carries no time thresholds and no medical decision-making levels, unlike office E/M codes 99202 through 99215. Some references describe it as a moderate-complexity encounter that varies with time spent, which applies problem-oriented E/M language to a preventive code and sends billers looking for a threshold that doesn't exist.

What is the difference between 99385 and 99395?

Both cover ages 18 to 39 with the same documentation requirements. 99385 applies to new patients, and CPT code 99395 applies to established ones. A patient counts as established if the physician, or the same specialty in the same group, provided professional services within the past three years. The 99395 CPT code description differs from 99385 in patient status only.

Can 99385 and 99204 be billed together?

Yes, when the provider addresses a significant, separately identifiable problem alongside the preventive visit. Modifier 25 goes on 99204, never on 99385, and the record must show distinct work for each service. Some payer systems carry an edit denying two new patient visits on the same date of service. That edit is appealable with the CPT reference attached.

Does Medicare cover 99385?

No. Routine physical exams fall outside Part B by statute. CMS instructs providers not to bill 99381 through 99397 for Medicare wellness services. Use G0402 for the Initial Preventive Physical Exam within the first 12 months of Part B enrollment, G0438 for an initial Annual Wellness Visit, or G0439 for subsequent visits. Medicare Advantage plans set their own rules and require verification.

What ICD-10 code goes with 99385?

Z00.00 covers a general adult medical exam without abnormal findings. Z00.01 covers one with findings. Under FY2026 ICD-10-CM guidelines, an exam revealing an abnormality requires Z00.01 sequenced first and a secondary code identifying the finding. Placing a chronic disease code in the primary position converts the claim to problem-oriented in the payer's adjudication logic and forfeits the preventive benefit.

What documentation is required for 99385?

Five components: an age and gender appropriate history, a comprehensive physical examination, counseling and anticipatory guidance, risk factor reduction interventions, and orders for appropriate laboratory or diagnostic procedures. All five must appear in the note. Counseling recorded as a checkbox is the most frequent audit failure in this code family, because a reviewer can't confirm the service happened from a checked box.

How often can 99385 be billed?

Once per patient relationship. It's a new patient code, so subsequent preventive visits move to 99395. The annual frequency limit governs that established patient code, applied as either a calendar year reset or a rolling 365-day interval depending on the payer. Billing before the interval elapses produces an automatic denial that survives appeal, because the dates settle it.

Getting CPT 99385 Right the First Time

Two variables select the code: the patient's age on the date of service, and whether your practice has seen them in the past 36 months. Everything else in this guide sits downstream of getting those right.

After that, the note carries the claim. All five components documented, and preventive work kept separate on the page from problem-oriented work when both go out on the same date.

Payer rules finish the job. Medicare won't pay this code, and commercial frequency models split between calendar year and rolling 365 days. For the established patient side of the same age logic, our established patient equivalent guide covers 99396 in the same depth.

When preventive denials show up as a pattern instead of an occasional error, the problem usually sits upstream of coding. Working the root cause before the next billing cycle costs less than working the same denials twice.

This guide is reviewed and maintained by the MedSole RCM coding and billing team. Content is updated when CMS, AMA, or payer policy changes.

About the Author
Andrew Christian

Andrew Christian

Billing Manager

Andrew Christian is the Billing Manager at MedSole RCM, bringing 12+ years of experience in medical billing, coding, and revenue cycle management across multiple specialties. He is highly skilled in claims submission, denial management, payment posting, and payer follow-up, ensuring maximum reimbursement for providers. Andrew works closely with Medicare, Medicaid, and commercial payers, supporting hundreds of providers nationwide. His proven billing approach minimizes claim rejections, accelerates cash flow, and drives stronger financial performance from day one.